Now that mal is dead, much like clarke what are they going to do with her, her backstory seems to have been confided to certain subjects-muse for malivore, fall for leonardo, trapped in pandoras orb and then released. So we were told in a spoiler her time in malivore will leave her changed cause of confronting past demons, well I think its time she finally finds out who killed her family in that fire. Um if I had to guess what will happen is time travel is going to be introduced, cleo will go back in time and idk if she can or cant interfere but see who set her familys house on fire and go to get vengeance on that person if they still live. Now onto who they maybe, personally I can already see malivore getting that revenge but by sending someone to do it, its highly possible he sent the vitruvian man since he was the last creation cleo made for him, idk if malivores other failures will ever come into play I have theories on all that but it wouldnt shock me the least bit if its clarke, he sends clarke to go kill her family to go in his good graces. If not clarke then someone else but the lack of casting announcements implies it could be him.