I agree with Nyxus123 on this. Of course there is a way to kill Hope, Cleo found it, I also think she is not unstoppable, but I still think she if more powerful than any creature. Her birth was magic event that Davina used to resurrect Mikael, nature itself reacted to her full transformation into tribrid. And whole supernatural world was afraid of her birth and what she can do. So, yeah, I think she more powerful than any creature and that mean she is not easily killed, but not impossible, I have to guess by only one way to do it. Of course she can be knocked unconscious, beaten etc but not killed for good by some hybrid (Valerie) or by staking or something like that, otherwise she wouldn't this powerful and terrifying to everyone, include nature.