<p>Silas: Qetsiyah was powerful enough to create the cure, so the witches would need to do is get the element of surprise, telekinetically break his neck, feed him the cure, then kill him. It’d be tricky though since he has very powerful mental powers.</p><p>
</p><p>The Beasts: Freya already created a dagger that was capable of killing Marcel. As for Lucien, Qetsiyah was particularly skilled at dessicating Immortals, so that would render him immobile for a while. Regular Originals can be killed with the power of 100 witches, and since Lucien is superior to regular Originals, I’d say you’d need the power of roughly 150-200 witches to kill him. Bonnie’s power is equivalent to 100 witches, The Hollow is stronger than Bonnie, so those two already would have the combined power of 200+ witches, which would be more than enough to kill Lucien considering you also have to add in Dahlia and Qetsiyah. </p><p>
</p><p>Cade: This would be a never ending battle because none of them have the means to kill each other. The witches don’t have access to the Bone Dagger and Cade’s hellfire can easily be held back by Bonnie alone, so when you add in Dahlia, Inadu, Esther, Freya, Hope, & Qetsiyah, they can easily hold off his hellfire.</p><p>
</p><p>Kai and Heretics: The Heretics might be able to siphon Bonnie, Qetsiyah, Hope, and Freya, since they are mortal, but they won’t be able to siphon the Hollow because they have nowhere to put her and her magic would slowly overrun their body and corrupt them. The Hollow can easily telekinetically rip out their hearts or decapitate them. </p><p>
</p><p>Rayna: She’s immune to offensive magic, but I think boundary spells work on her, so they can lock her up in a boundary spell and physically kill her 8 times.</p><p>
</p><p>The Travellers: Qetsiyah was already stated to be the most powerful out of the Traveller subculture, so when you add in all the other witches, they’d easily tear the Travellers apart.</p><p>
</p><p>The Ancestors: The Hollow’s followers stated that Inadu herself was superior tothe Ancestors, so..</p><p>
</p><p>Strix: Hope, when amplified with Inadu’s power, killed all the Nazi vampires in one fell swoop, I’m sure they could do the same to the Strix. While the Strix are older and stronger than the Nazi vamps, you also have to consider Qetsiyah, Bonnie, and Dahlia as well.</p><p>
</p><p>Katherine: As a vampire, they can easily kill her with offensive magic. As the queen of hell, it’d be the same as Cade.</p><p>
</p><p>The Originals: Snap their necks, feed Rebekah the cure, then take her blood and feed it to Finn, then take his blood and feed it to Kol, then take Kol’s blood and feed it to Klaus, then take Klaus’ blood and feed it to Elijah. Once they’re all mortal, kill them with offensive magic.</p><p>
</p><p>Sirens: Same thing as Katherine, only Cade is able to kill the Sirens.</p>