Cedeño was born in Moses Lake, Washington, to an Afro-Cuban father and an Irish-English mother. He became a model doing gigs in Milan, Spain, New York and Los Angeles, which Cedeño juggled, along with academics, until he finished school. Cedeño married Erica Franco on July 31, 2009, and their son, Jaxson Cruz, was born on August 7, 2013.
Cedeño is known for his role as Brandon Walker on the NBC daytime soap opera Days of Our Lives from 1999 to 2005. He has been nominated three years in a row for an ALMA award as Outstanding Actor in a Daytime Drama for his work as Brandon Walker on NBC's Days of our Lives. He played a young boxer in the 2000 feature film Price of Glory (Jimmy Smits plays the same character years later). He guest-starred on Boy Meets World, CSI: Miami, It's Always Sunny in Philadelphia, and The Mentalist.
Cedeño appeared on the one hundredth episode of ABC comedy-drama series Desperate Housewives as Umberto Rothwell, the gay husband of Edie Britt (Nicollette Sheridan). In 2013, he had a recurring role in the Lifetime comedy-drama Devious Maids during season 1 and part of season 2, playing another gay character called Alejandro Rubio. However, his character was killed off in season 2.
He currently stars in the Syfy television series Z Nation and also stars as Cristobal in Starz's Power show.
- He was formerly a model.
- Has an older brother named Ray and a half brother named Scott.
- His father is Black Cuban and his mother is of Irish and English heritage.
- He's a fan of Billy Joel, Janet Jackson, Celia Cruz, and some hip hop.